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  • Preclinical

Open near infrared fluorescence imaging

The LightIR is an open fluorescence imaging device designed for preclinical fluorescence imaging or clinical research. 


Vascular imaging in mouse after injection of NIR-II fluorescent nanoparticles

Key Features:

1. Near infrared fluorescence and NIR-II fluorescence

2. Preclinical studies, or clinical studies under IRB approval

3. Small or large animals

List of common fluorescent moieties used with the LightIR:

  • Cy5, Cy5.5, Cy7, IRDye 700 and IRDye 800 from LiCOR, Indocyanine Green (ICG), ZW 800
  • Rare earth (lanthanides), quantum dots and various fluorescent nanoparticles
  • The various IVISense fluorescent agents (680, 700, 800)
  • Alexa Fluor AF 680, AF 700, AF 750, AF 790
  • infrared fluorescent protein: iRFP

Near infrared and NIR-II fluorescence

  • Limited autofluorescence
  • Great depth penetration
  • Better resolution

NIR-II fluorescence (900 to 1650 nm)

  • Virtually no autofluorescence
  • Imaging through skull, bone, melanin (melanoma studies)

Product Specifications

TECHNICAL SPECIFICATIONS
Imaging modes NIR-I or NIR-II fluorescence, brightfield, subtracted, overlay. Optional: RGB brightfield
Real-time processing Background subtraction, brightfield/fluorescence overlay
Emission spectral range NIR-I : 650 - 900 nm, NIR-II : 900 - 1600 nm
Fluorescent channels 1 or 2 channels
Available excitation wavelengths 640 nm, 690 nm, 750 nm, 785 nm, 808 nm, 980 nm
Emission filters Set according to chosen excitation wavelengths
Field of view 7 cm x 7 cm
Detector CMOS (NIR-I) or Alize 1.7 InGaAs (NIR-II)
Image size (px) 1024 x 1024 (NIR-I) or 512 x 512 (NIR-II)
Output format TIFF images (16 bits) with metadata

Publications

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