ACS Applied Bio Materials
- Préclinique
Duplex Phenotype Detection and Targeting of Breast Cancer Cells Using Nanotube Nanoprobes and Raman Imaging
Auteurs Suraj Mal, Layane Duarte e Souza, Charlotte Allard, Carolane David, Sébastien Blais-Ouellette, Louis Gaboury*, Nathalie Y.-W. Tang, and Richard Martel
Résumé
Find out more about the design, synthesis and demonstration of a novel Raman nanoprobe made of dye-sensitized single-walled carbon nanotubes (SWCNTs) to selectively target biomarkers of breast cancer cells. Using hyperspectral Raman imaging, S. Mal et al. from the group of Prof. R. Martel, Department of Chemistry at University of Montreal were able to perform simultaneous detection of two distinct nanoprobes that specifically recognize biomarkers on breast cancer cells without the need for additional filters or subsequent incubation steps.