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PRODUCTS |  IR VIVO™

CHARACTERISTICS          SPECIFICATIONS          APPLICATIONS          PUBLICATIONS          RELATED PRODUCTS         VIDEO

 

An unprecedented combination of fast acquisition speed, multicolour imaging, high spatial resolution and penetration depth allows seeing both structure and function.

Photon Etc.'s preclinical infrared imager is a multispectral infrared imaging system for in vivo studies in small animals or living organisms. IR VIVO™ offers multispectral imaging using a filter wheel and hyperspectral imaging with a continuously tunable spectral range from 850 nm to 1620 nm and a spectral resolution of < 4 nm. By virtue of high-efficiency filters and high-speed scientific grade SWIR cameras,  IR VIVO™ can accurately isolate the emission of several IR labels. The imager provides the perfect tool for all applications that involve detection in the second biological window.

 

NIR-II IMAGING PROPERTIES

  • Non-ionizing & non-invasive

  • High spatial resolution

  • Probes for multispectral imaging

  • Intrinsic contrast

  • Functional imaging

  • High temporal resolution = Real-time dynamics

  • Good penetration depth (10x greater than traditional optical systems) 

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PRODUCT SPECIFICATIONS 

IR VIVO™
EMISSION SPECTRAL RANGE  

850 - 1620 nm
Extension available in the visible up to 400 nm
FILTER TYPES   Multispectral: Filter wheel
Hyperspectral: HyperCube™
HYPERCUBE SPECTRAL RESOLUTION  < 4 nm
ILLUMINATION SOURCE  

730, 780, 808 or 810 nm LEDs
Other sources available upon request
ILLUMINATION AREA   15.6 x 12.5 cm field of view for 3 mice model
FIELD OF VIEW   variable from 5 x 4 cm to 15.6 x 12.5 cm
OVERALL INSTRUMENT   DIMENSIONS  

Tabletop
About 75 x 115 x 75 cm
STAGE TEMPERATURE   Up to 40ºC
ANESTHETIC TUBING AND   NOSECONE   3-mice anesthetic gas manifold supplied
COMPUTER   PC with Windows 7-64 bits included
IMAGING SOFTWARE   PHySpec™ software
SPECTRAL DATA FORMAT  HDF5, FITS
SINGLE IMAGE DATA FORMAT  HDF5, CSV, JPG, PNG, TIFF
   
POWER REQUIREMENT   120 VAC / 12 A / 60 Hz
ACQUISITION MODE AVAILABLE   Unfiltered (Broadband)
VIDEO MODE   Megapixel camera for sample visualization

----  CAMERA  ----
TYPE   InGaAs (ZephIR™ 1.7)
FPA  

640 x 512 pixels
PIXEL SIZE   15 µm
QE   < 75%
DYNAMIC RANGE   13/15 bits

The penetration depth depends on the sample properties.

APPLICATIONS

EXAMPLES OF NIR-II IMAGING APPLICATIONS

  • Identify cancer tissue

  • Monitor blood flow & metabolic imaging

  • Monitor cell environment (pH, lipid, mRNA)

  • Monitor healing of burns & perfusion

  • Monitor heart and respiratory rates contact-free

  • Tumour imaging to guide real-time surgeries

  • Visualize microvasculature​

 

IDEAL FOR:

  • All in vivo applications involving detection in the second biological window

  • Drugs, toxicology, diagnostic, IR tracers and labels development studies

  • The evaluation of oxygenated versus deoxygenated blood ratios

  • Nanoparticles distribution​​

PUBLICATIONS

INSIGHT FROM THE INDUSTRY - IR VIVO
USING PRE-CLINICAL IMAGING TO DETECT CANCER
By Émilie Beaulieu-Ouellet, Application Scientist in Life Science

In this interview, Émilie Beaulieu Ouellet talks about the recently released and breakthrough imaging system: the IR VIVO™ and its technology. Photon etc.’s IR VIVO™ system is the first and only turnkey hyperspectral preclinical imager optimized for imaging in the second biological window of the near-infrared (NIR-II) / short-wavelength infrared (SWIR) range available on the market to our knowledge. NIR-II imaging will bring an unprecedented combination of fast, high resolution and penetration depth imaging at lower cost and to a broader community than current preclinical imaging techniques. Altogether, it will enable to resolve and track single biomedical targets or processes throughout small animals, thereby opening a new window of possibilities for fundamental and biopharmaceutical research.

READ THE INTERVIEW

RELATED PRODUCTS

ZEPHIR™ 1.7

ZephIR™ 1.7 is an affordable scientific-grade near-infrared InGaAs camera, highly sensitive from 0.8 to 1.7 µm. A four-stage TE cooler, deep-cooling at -80°C, provides unrivalled low-noise levels at an astounding 200 frame-per-second rate.

HYPERCUBE™

The HyperCube™ will transform your microscope, camera or a vast variety of excitation modules into a high resolution spectral imaging system, opening new research perspectives in biological imaging. 

VIDEO

Photon etc.'s Global Imaging Technology

This video shows the conceptual difference between hyperspectral global imaging and raster scan (line-scan, push-  broom). With global imaging, the gain in acquiring 3D data, 2D  spatial and 1D spectral, is important since the only a few monochromatic images are required to cover the complete spectral range where one needs to take the full spectrum for each point or line in the image with other technologies.

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